Saratov JOURNAL of Medical and Scientific Research

Nugaeva N.R.

Saratov State Medical University n.a. VI. Razumovsky, Clinic of Eye Diseases, Ophthalmologist, Candidate of Medical Science

Computer analysis of corneal aberrations in relation to the tasks of laser surgery of the anterior segment of the eye

Year: 2019, volume 15 Issue: №2 Pages: 425-428
Heading: Ophtalmology Article type: Original article
Authors: Bakutkin V.V., Bakutkin I.V., Zelenov V.A., Nugaeva N.R.
Organization: International Consulting, Audit and Education Academy, Saratov State Medical University
Summary:

Purpose: development of a method for computer analysis of corneal aberrations as applied to the tasks of laser surgery of the anterior segment of the eye. Material and Methods. As a result of mathematical modeling, an algorithm has been developed that is implemented as a computer program for selecting individual parameters of laser radiation depending on the optical characteristics of the cornea. Results. For astigmatism, it has been proposed to consider the topographic zones of the optical center of the cornea, 3.5 mm in diameter, and peripheral meridional zones. Aberrations at the periphery of the cornea increase by 10 %. At 1 and 2 stages of keratoconus, the rate of aberrations rises 2–3 times. In the third stage of keratoconus, in some cases keratometry and keratotopography is technically impossible. With pterygium 2 and 3 degrees, laser surgery in the peripheral zone of the cornea is impossible. Conclusion. Improving the efciency of laser operations is provided primarily by optimizing the impact parameters on the tissues of the anterior segment of the eye. The data on the types of corneal aberrations for various diseases, which indicate the need to change the parameters of laser exposure. The developed diagnostic algorithms are implemented as a computer program and allow you to optimize the parameters of laser irradiation of eye tissue.

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Fluorescent angiography and optical coherence tomography with angiography of the ocular fundus in patients with "the wet" form of an age-related macular degeneration.

Year: 2017, volume 13 Issue: №2 Pages: 345-349
Heading: Ophtalmology Article type: Original article
Authors: Virsta A.M., Kamenskikh T.G., Nugaeva N.R., Kolbenev I.O., Gileva E/V.
Organization: Saratov State Medical University
Summary:

Purpose: to investigate the informative value of fluorescent angiography (FA) and optical coherence tomography with fundus angiography (angio-OCT) in the diagnosis of "wet" form of age-related macular degeneration (AMD). Material and methods. The present study included 20 patients (20 eyes) diagnosed with degeneration of macula and posterior pole of the eye, the "wet" form (late stage age-related macular degeneration, AREDS category 4). The study used machines: optical coherence tomography, Spectralis HRA+OCT (Heidelberg Engeneering, Germany), optical со- herence tomography-angiography CIRRUS HD-OCT MODEL 5000 (Carl Zeiss, Germany). Results. When conducting the FA, in 11 patients found the ill-defined zone of small leakage of dye in 7 patients revealed a clearly defined area of hyperfluorescence in the early phase, and marked leakage of dye in the late phase, 2 patients — uncertain indices. In connection with the received data questionable PHAGE in 11 patients, all were held angio-OCT, to clarify the localization of choroidal neovascularization (CNV). When performing angio-OCT in 11 patients revealed that "wet" form of AMD with occult choroidal neovascularization. In 7 patients there had been discovered classic CNV in 2 patients combined. Conclusion. Angio-OCT gives a clearer picture about the presence of a choroidal neovascular membrane that plays a significant role in determining the course of treatment of patients with wet age-related macular degeneration.

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