Saratov JOURNAL of Medical and Scientific Research

Bobylev D.A.

Saratov State Medical University n.a. V I. Razumovsky, Department of Roentgen Diagnostics and Radiotherapy n.a. N. E. Shtern, Assistant

Radiation methods for evaluating renal function in children

Year: 2018, volume 14 Issue: №3 Pages: 385-388
Heading: Radiology Article type: Review
Authors: Chekhonatskaya M.L., Averianov А.Р., Uts I.A., Velikanova M.G., Bobylev D.A., Chekhonatsky I.A.
Organization: Clinical hospital n.a. S. R. Mirotvortsev SSMU, Russian Medical Academy of Postgraduate Education, Moscow, Saratov State Medical University

 An accurate assessment of renal function is critical for adequate dosing of medications. The most informative marker reflecting the functional state of the kidneys is glomerular filtration rate (GFR). Determination of inulin clearance is the most accurate way to assess GFR in children and adults. In this case, the method is invasive, cumbersome, younger children require the installation of a urinary catheter. Techniques for radioisotope estimation of GFR can solve this problem, but all widely used radioisotopes have the ability to bind slightly to plasma proteins, which leads to an underestimation of real values.

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A comprehensive approach to the diagnosis and treatment of straghorn nephrolithiasis

Year: 2018, volume 14 Issue: №1 Pages: 81-86
Heading: Urology Article type: Review
Authors: Chekhonatskaya M.L., Rossolovsky A.N., Kryuchkov I.A., Bobylev D.A.
Organization: Saratov State Medical University

A review of the literature is devoted to the most topical diagnostic questions and treatment of patients with urolithia-sis. The role and the latest advances and benefits of minimally invasive surgery were described. Particular attention was paid to the problems of residual calculi and the condition of the renal parenchyma in the perioperative period. The theme of choice of conducting such patients tactics was considered. The actual diagnostic methods and a differentiated approach to the algorithm choice of the examination and treatment of patients with staghorn nephrolithiasis were considered. The review provided a scientometric analysis of research information (documents reference), contained the analytical array of scientific publications. Electronic information resources of scientific electronic library bibliographic databases: eLibrary, PubMed, Clinical Key, Science Direct — were used.

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Correlation between size and density indices of concrements in patients with nephrolithiasis and effective method of treatment by distance shock-wave lithotripsy

Year: 2017, volume 13 Issue: №1 Pages: 77-81
Heading: Urology Article type: Original article
Authors: Chekhonatskaya M.L., Rossolovsky A.N., Bobylev D.A.
Organization: Saratov State Medical University

The aim of the article: evaluation of the results of treatment of patients with nephrolithiasis by distance shock-wave lithotripsy on the basis of the data on kidneys received from multispiral computed tomography. Material and Methods. The study involved 46 patients who were hospitalized in the clinic of urology with diagnosed urolithiasis with the pres- ence of a renal calculus from 10 to 17 mm in size. A complex of laboratory analyses including multispiral computed tomography was used. The concrement elimination was carried out by distance shock-wave lithotripsy Results. Correlation analysis and ROC-analysis did not show the efficacy of distance shock-wave lithotripsy comparing scanning procedures and distance shock-wave lithotripsy. Conclusion. The size and average density of a concrement according to multispiral computed tomography should not be served as a basis for prognosis of effective fragmentation of concre-ments by distance shock-wave lithotripsy in patients with urolithiasis caused by stones of 10-17 mm in size.

2017_01_077-081.pdf548.75 KB