Saratov JOURNAL of Medical and Scientific Research

First Moscow State Medical University n.a. I.M. Sechenov

Anatomy of the posterior communicating artery

Year: 2018, volume 14 Issue: №1 Pages: 25-29
Heading: Human anatomy Article type: Review
Authors: Fomkina О.А., Nikolenko V.N., Gladilin Yu.A.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

Purpose: to generalize and systematize the information available in the literature about the anatomy of the posterior connective arteries in adults. Scientific works (monographs, articles, dissertations and abstracts of dissertations) of native and foreign authors for the period from 1928 to 2017 were worked out to achieve the goal. Data on the variants of artery discharge, areas of blood supply and major anomalies are presented. The size characteristics of arteries (length, outer diameter, wall thickness and lumen diameter) are presented taking into account bilateral, age and sexual differences.

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Biomolecular assessment of renal function in various types of surgical treatment of renal cell carcinoma

Year: 2017, volume 13 Issue: №1 Pages: 73-77
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Popkov V.M., Tarasenko A.l., Maslyakova G.N., Rossolovsky A.N., Zakharova N.B., Berezinets O.L., Lomakin D.V.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

Objective: to assess the possibility of using the markers of acute kidney injury to predict the preoperative risk for the subsequent decline in glomerular filtration rate in different types of surgical treatment of renal cell carcinoma (RCC). Material and methods. 60 patients with histologically confirmed RCC T1-3M0N0 operated in the clinic of urology of Saratov State Medical University n.a. V. I. Razumovsky in the volume of nephrectomy or partial nephrectomy. Before surgery all patients underwent standard examination intended for patients with kidney tumors: ultrasound, MRI, excretory urography and dynamic renoscintigraphy, the perioperative values of serum creatinine and glomerular filtration rate were determined. Using the method of immuno-enzymatic analysis the concentrations of excreted with the urine NGAL and IL-18 in serum samples at the preoperative stage, after 5 days and after 1 month of postoperative follow-up were investigated. Differences in clinical data and clinical variables were compared by using Spearman rank correlations and t-test. Results. The determined parameters of acute kidney injury markers IL-18 and NGAL in the early postoperative period were increased in patients after open nephrectomy. Moreover, the correlation analysis according to the Spearman method revealed a strong significant correlation between the preoperative levels of IL-18 and GFR after surgery (r=1; p<0.05). Conclusion. Laparoscopic resection of RCC is the method of choice for surgical treatment of RCC. As a predictor of adverse prognosis, the level of IL-18 in serum may be used. Its increase correlates with a decline in renal function in the postoperative period, and according to some reports, IL-18 also is an independent predictor of adverse prognosis in patients with a localized RCC.

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Parkinson's disease in Russia: prevalence and incidence

Year: 2016, volume 12 Issue: №3 Pages: 379-384
Heading: Neurology Article type: Review
Authors: Razdorskaya V.V., Voskresenskaya O.N., Yudina G.K.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

The results of the regional studies on the frequency of Parkinson's disease (PD) and the incidence of it in Russia have been generalized, the main factors that determine the quality of the estimates of this disease epidemiological indicators have been identifyd. The article summarizes data from 19 original studies on the epidemiology of parkinsonism and Parkinson's disease in Russia published between 2005-2015. Due to the statistical heterogeneity of the primary results computational analytics was not applied to the data; however, data consolidation allowed to perform a trend analysis of epidemiological indicators. The methodological basis of the majority of studies was medical aid appealabil-ity; two of the studies used door-to-door surveys. One of the studies returned questionably low epidemiological indicators obtained from the medical records, and the rest showed the standardized prevalence of 30.0-139.9/100,000 and incidence of 7.63-21.8/100,000 per year. Contribution of Parkinson's disease to the nosological structure of parkinsonism was >61.3%. Estimate of the number of patients with PD in Russia is approximately 210,000 people. Conclusions are made regarding the prevalence of PD in Russia according to the cross-cutting research on the level of indicators in the Western countries. The prevalence of PD by appealability is 2-3 times less than the prevalence in continuous research, both national and foreign. The incidence of PD, demonstrated in half of the studies, is stable from region to region and is comparable with the universally recognized values.

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Anatomy of sphenoid part of middle cerebral artery in adults

Year: 2016, volume 12 Issue: №1 Pages: 15-18
Heading: Macro- and Micromorphology Article type: Review
Authors: Fomkina О.А., Nikolenko V.N., Gladilin Yu.A.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

The information about anatomy of middle cerebral artery in adults has been summarized on the basis of data analysis of domestic and foreign scientific literature. Material concerning options for arteries discharge, area of blood supply, major anomalies and size characteristics (outer diameter, wall thickness, lumen diameter) has been represented in this work.

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The interrelation between length parameters of the proximal phalanges and the middle and distal phalanges of the 2-5th fingers

Year: 2015, volume 11 Issue: №3 Pages: 247-249
Heading: Macro- and Micromorphology Article type: Short message
Authors: Bikbaeva T.S., Aleshkina O.Yu., Nikolenko V.N. Fomkina O.A.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

Objective: to determine the volume and direction of correlations of length of the proximal phalanges of the 2-5th fingers of the hand with osteometric parameters of phalanges of like fingers. Material and Methods. The length of proximal, medium and distal phalanges, as well as the width and height: the bases, body and heads (distal tuberosity) phalanges of fingers of the hand were studied on 150 skeletons of adult men and women hands at the age 21-90 years old. Results. The correlation between the length of proximal phalanges and pulse- high-rise parameters of proximal, medium and distal phalanges of 2-5th fingers of hand was determined. Conclusion. The length of the proximal phalange forms a different strength and direction of the correlation. The lengths of the proximal phalanges have a positive direction of moderate strength with all parameters of middle phalanges and the average degree of correlation with the length of the distal phalanges, the width of its base and the body.

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Variability of morphometric parameters of feet in various forms of lower extremities

Year: 2014, volume 10 Issue: №4 Pages: 600-603
Heading: Macro- and Micromorphology Article type: Original article
Authors: Konnova O.V., Aleshkina O.Yu.l, Nikolenko V.N.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University
Summary:

Purpose: to identify the various forms of lower extremities variability of linear and angular parameters of feet in girls aged 17-19 years. Material and Methods. The object of the study included 242 students from Saratov State Medical University, 17—19 years. Foot digital plantography photometric device-software complex «Plantvizor» and measuring distances between sibling points of lower extremities to highlight their forms have been used as a method of research. Results. 8 forms of lower extremities, among which half per cent occurs in isolated form, valgus-direct from the mil-lennim clearance opening and a trapezoidal shape of lower extremities varus. In all forms of lower extremities morphometric parameters of feet and ratio of statistically significant differences in various forms of lower extremities have been studied. Conclusion. Anatomical basis for operational adjustment of axial disorders of tibiae and its influence on morphofunctional state of foot can be resulted from the study.

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The combined use of pelotherapy and phytocomplex in rehabilitation of patients with knee joint osteoarthrosis

Summary:

Aim: to study the effect features of combined use of pelotherapy and phytocomplex on main clinical symptoms regress and quality of life in patients with knee joint osteoarthrosis. Material and Methods. The study included 96 patients with knee joint osteoarthrosis; the effectiveness evaluation was estimated in terms of American Rheumatologic Association (ARA), the data of visual-analogue scale (VAS), goniometry and laser Doppler flowmetry, indexes WOMAC, Lekena and the index of activity SIA, criteria of life quality questionnaire HAQ. Results. The complex use of pelotherapy and phytocomplex in conjunction with a drug treatment of patients have a more pronounced positive effect on pain (by 35-36%), function of the knee joint (by 26-28%), microcirculation (1.5-2 times) and the quality of life (by 22-25%) compared to treatment with only drug treatment or combined using of ultrasound and drug therapy. Conclusion. The new method of combined use of pelotherapy and phytocomplex leads to the evident regress of clinical symptomatology at patients with knee joint osteoarthrosis, improves locomotor function, microcirculation of knee joints and quality of life.

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Efficiency assessment of phytocomplex phonophoresis in rehabilitation of patients with knee joint osteoarthrosis

Summary:

Objective: the comparative research of phytocomplex phonophoresis rehabilitation efficiency of patients with knee joint osteoarthrosis. Material and Methods, the study included 100 patients with knee joint osteoarthrosis; the effectiveness evaluation was made in terms of American Rheumatologic Association (ARA), the data of visual-analogue scale (VAS) and goniometry, indexes WOMAC, Lekena and the index of activity SIA, criteria of life quality questionnaire HAQ. Results. The complex use of phyto- and ultrasonic therapy in conjunction with an medicamentous treatment of patients have a more pronounced positive effect on pain (by 26-28%), function of the knee joint (by 22-26%) and the quality of life (by 24%) compared to treatment with medicamentous only treatment or combined using ultrasonic and medicamentous therapy. Conclusion. The new method of phytocomplex phonophoresis leads to the expressed regress of clinical symptomatology at patients with knee joint osteoarthrosis, improves locomotor function of knee joints and quality of life.

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Oral surgical treatment by erbium laser application in patients with the risk of bleeding

Year: 2013, volume 9 Issue: №3 Pages: 477-480
Heading: Traumatology and Orthopedics Article type: Original article
Authors: Tarasenko S.V., Makarova Е.V., Melikyan A.L.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Hematology Scientific Centre
Summary:

Aim: to analyze the erbium laser effects in oral surgery in patients with the risk of bleeding. There were selected 2 groups of patients for oral surgery treatment. Materials and methods. The first group included 31 patients with bleeding risk. In this group erbium laser radiation was used for the cut and tooth socket conditioning after tooth extraction. The second (control) group of 43 patients without concomitant pathology was determined for conventional surgical treatment. Results. In the first group there was no postoperative bleeding, post-surgical pain and infection were prevented with no need for analgesics, and the wounds epithelization took 1-3 days. It takes less time than in control group. Conclusion. Application of erbium laser is a modern method which can be successfully used in surgical treatment of patients with the risk of bleeding.

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The role of epithelial cells proliferation and apoptosis disturbances in pathogenesis of inflammatory diseases of parodentium accompanied by gastroesophageal reflux disease

Year: 2013, volume 9 Issue: №3 Pages: 449-453
Heading: Stomatology Article type: Original article
Authors: Osipova J.L., Bulkina N.V., Osadchuk М.А., Kvetnoy I.M.
Organization: First Moscow State Medical University n.a. I.M. Sechenov, Saratov State Medical University, St. Petersburg Institute of Bioregulation and Gerontology
Summary:

The aim of the research was the study of the cell proliferation indices of the gum epithelial cells in patients with parodentium inflammatory diseases accompanied by gastroesophageal reflux disease (GERD). Material and methods. 160 patients were examined, 60 patients with parodentium inflammatory diseases accompanied by NEGERD, 40 patients with parodentium inflammatory diseases accompanied by GERD. The comparison groups consisted of 40 patients with diseases of parodentium without esophagus pathology and 20 healthy persons. Results. On the basis of the conducted clinical-endoscopic, immune-histological and morphological examinations it was established that gingivitis and periodontitis are successive stages of disturbance of the cellular homeostasis of gum epithelial cells. Conclusion. The enhancement of the processes of proliferation and apoptosis promotes the progression of the structural alterations in the tissues of parodentium and oesophagus and may serve as additional diagnostic and prognostic criteria of the diseases of parodentium accompanied by GERD.

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