Saratov JOURNAL of Medical and Scientific Research

magnetic resonance tomography

Magnetic resonance imaging and biomarkers of serum and urine wile diagnostics of kidney cancer

Year: 2016, volume 12 Issue: №1 Pages: 52-56
Heading: Parmacology Article type: Original article
Authors: Nickolsky Yu.Ye., Chekhonatskaya M.L., Zakharova N.B., Popyhova E.B., Ponukalin A.N.
Organization: Saratov State Medical University
Summary:

Purpose: improvement of differential diagnostics of benign and malignant renal tumors basing on complex estimation of the results of MRTand the level of such biomarkers as vascular endothelial growth factor, monocyte chemotactic protein-1 and matrix metalloproteinase-9 in blood serum and urine. Material and Methods. A total of 106 patients including the main group of 60 patients with renal cancer (RC), the group of comparison of 16 patients with benign renal tumors and the control group of 30 practically healthy persons were examined. ELISA was employed for detection of the biomarkers in blood serum and urine. The tumors were diagnosed by MRT Results. The increase of the level of the biomarkers in blood serum and urine was registered independently of the character of neoplastic process; more significant increase was observed in patients with RC, especially at the early stages of the disease. Some peculiarities of changing of the level of the biomarkers depending on the dimensions of malignant tumors were found. Conclusion. At the early stages of RC complex detection of the abovementioned biomarkers in blood serum and urine can serve an additional clinical diagnostic and prognostic criterion.

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Radiology in diagnostics of odontogenic maxillary sinusitis

Year: 2013, volume 9 Issue: №3 Pages: 486-489
Heading: Stomatology Article type: Original article
Authors: Chekhonatskaya М.L, llyasova Е.В., Konnov V.V., Priezzheva V.N., Kochanov S.V., Khmara T.G., Arushanian A.R.
Organization: Saratov State Medical University
Summary:

The purpose: to prove diagnostic capabilities of modern radiation techniques in odontogenic maxillary sinusitis. Material and methods: The study involved 546 patients with sinusitis. The following methods have been used: X-ray of the paranasal sinuses, contrast maxillary sinus radiography, contact intraoral radiographs, orthopantomography, computer tomography and magnetic resonance imaging. Results. In 7,9% of cases the presence of odontogenic sinusitis has been established, in 92,1 % rhinogenous sinusitis has been revealed. The work provides information about the effectiveness of various radiation techniques in the diagnosis of odontogenic sinusitis. Conclusion. For suspected odontogenic sinusitis, treatment of choice includes the combined use of X-ray of the paranasal sinuses in the mentoanterior projection and contact intraoral radiographs of «causal teeth». Computer tomography is the most informative additional method to clarify the diagnosis of odontogenic sinusitis.

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Chronic pyelonephritis in pregnancy

Year: 2012, volume 8 Issue: №4 Pages: 920-925
Heading: Obstetrics and Gynecology Article type: Review
Authors: Minasyan A.M., Dubrovskaya М.V.
Organization: Saratov State Medical University
Summary:

В обзоре литературы анализируются актуальные проблемы такого опасного заболевания, как пиелонефрит, диагносцируемый у беременных и родильниц.

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Possibilities of magnetic resonance tomography in identification and diagnostics of neurosyphilis forms

Year: 2011, volume 7 Issue: №3 Pages: 647-652
Heading: Neurology Article type: Original article
Authors: Kolokolov O.V., Bakulev A.L., Zuev V.V., Sholomov I.I., Chekhonatskaya M.L, Kolesnikov A.I., Tikhonova LA., Starodubova A. V.
Organization: Saratov State Medical University
Summary:

Aim: To evaluate the possibilities of the magnetic resonance tomography (MRT) in diagnostics and identification of neurosyphilis. Materials and methods: A total of 1387 patients with different forms of documented neurosyphilis were examined to study the deficiency of neurological function. The diagnosis of neurosyphilis was confirmed by CSF-study. MRT was performed in 57 cases. Results: Magnetic resonance tomography (MRT) in 6 patients showed no pathology, 16 patients had arachnoid cystic changes and in 16 cases hydrocephaly occurred. Cerebral cortical atrophy was presented in 13 patients, in 12 cases — multifocal changes were visualized, 12 patients had white matter structural changes. Two cases required diagnostics. A 59-year-old man was hospitalized with epileptic seizure, progressive dementia and multifocal neurologic symptoms. A 40-year-old man was examined with recurring episodes of acute cere-brospinal accident and progressing cognitive disorders. Conclusion: MRT could be used in differential diagnostics of neurosyphilis imitating space-occupying lesions of cerebrum and spinal cord, tumors of central nervous system and could help to define the form of neurosyphilis

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Opportunities of radiological methods for examination in diagnostics of urinary bladder cancer

Year: 2011, volume 7 Issue: №1 Pages: 148-151
Heading: Urology Article type: Review
Authors: Glybochko P.V., Zuev V.V., Popkov V.M., Chekhonatskaya M.L, Ponukalin A.N.
Organization: Saratov State Medical University, First Moscow State Medical University n.a. I.M. Sechenov
Summary:

The research goal is the comparative analysis of Russian and foreign studies concerned the possibility of radiological methods of diagnostics of cancer of urinary bladder. The problem of early diagnostics of initial tumor and tumor recurrence, determination of stages of bladder cancer, its prognosis and outcome remains an actual one

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Comparative analysis of data of clinical, laboratory and radiation diagnostic techniques of prostate cancer with histomorphological tumor gradation by Gleason scale

Year: 2010, volume 6 Issue: №2 Pages: 446-453
Heading: Urology Article type: Original article
Authors: P.V. Glybochko, T.G. Hmara, V.M. Popkov, M.L. Chekhonatskaya, G.N. Maslyakova, V.N. Priezsheva, A.N. Ponukalin
Organization: Saratov State Medical University, First Moscow State Medical University n.a. I.M. Sechenov
Summary:

In scientific article the research goal is the comparative analysis of data of clinical, laboratory and radiation diagnostic techniques of prostate cancer with histomorphological tumor gradation by Gleason scale. the level of prostate-specific antigen (PSA) and index PSA D depend on parameters on Gleason scale. Ultrasonic findings are correlated with histomorphological gradation of adenocarcinoma. Magnetic-resonance imaging is effective only with 8-10 points on Gleason scale. In the research 217 patients with suspecting prostate cancer have been included. As a result prostate cancer has been diagnosed in 157 (72,4%) patients, prostate adenoma - in 60 (27,6%) patients

MAGNETIC RESONANCE TOMOGRAPHY AT CHOLECYSTITIS AND ITS COMPLICATIONS

Year: 2008, volume 4 Issue: №3 Pages: 139-141
Heading: Internal Diseases Article type: Short message
Authors: F.Z. Chanyshev, S.Sh. Dagayev
Organization: Moscow Research Institute for Endosurgery, Saratov City Clinical Hospital № 10
Summary:

The magnetic resonance tomography (MRT) was carried out for 53 patients with clinical presentations of cholecystitis.
Advantages of MRT in diagnostics of cholecystitis and its complications were studied: non-contrasting cholandiopancreatografy, with receiving of images in any projection, opportunity of carrying outof multiplanar reconstruction, intensive staining of soft tissues with receiving of three-dimensional images of bile tracts and absence of radiation sickness.

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