Saratov JOURNAL of Medical and Scientific Research

Saratov State Agrarian University named after N.I. Vavilov

Statistics and evidence-based medicine: health care supervisors realization in practice

Year: 2018, volume 14 Issue: №1 Pages: 007-011
Heading: Health Service Organization Article type: Original article
Authors: Yerugina M.V., Korshever N.G., Sidelnikov S.A., Baregamyan L.A.
Organization: Saratov State Agrarian University named after N.I. Vavilov
Summary:

The aim of the work is associated with investigation of realization of knowledge of statistics and evidence-based medicine in activities of health care supervisors. Material and Methods. There were used sociological, statistical and analytical methods of investigation. There has been carried out an anonymous questioning of 92 physicians-organizers during the process of their advanced training in the specialty "Health care organization and public health". Results. It has been established that in their practical work health care supervisors do not completely realize possibilities of both medical statistics and evidence-based medicine which is closely connected with medical statistics. The complex of reasons has been determined according to the situation. Health care organizers have been revealed to have low levels of knowledge of medical statistics (2,60±0,03 marks) and evidence-based medicine (2,32±0,03 marks). It has been demonstrated that during the course of advanced training in the specialty "Health care organization and public health" these levels and motivation of students may be significantly raised (3,79±0,05 and 4,13±0,06 marks). Conclusion. The obtained results of the investigation are recommended to be used both in practical activities of health care supervisors and in the process of their professional training.

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Mechanisms to solve the problems of social-ecological adaptation of students of higher school

Year: 2016, volume 12 Issue: №4 Pages: 619-621
Heading: Pedagogics and Education Article type: Short message
Authors: Lobanov V.G., Skvortsov Уu.I.
Organization: Saratov State Agrarian University named after N.I. Vavilov, Saratov State Medical University
Summary:

The purpose: studying of educational opportunities of sports tourism in processes of early social adaptation of students and gender features of ecological knowledge of students of higher education institutions of various profiles. Material and methods. Questioning of students of 2 and 3 courses of agrarian (n=147)and medical (n=147) of universities of Saratov age till 21 year in a gender ratio 1:1 is conducted. Results. Low ecological literacy of students of agrarian and medical universities, and also very "vague" ecological outlook is revealed. Gender distinctions in perception of environmental problems have been established. So, girls of medical university are more ecologically competent, than young men. Girls of both higher education institutions are more concerned about an ecological situation on the planet, but in too time a peculiar social and psychological mimicry which was shown in lack of correlation between the correct answers to questions of endoecology and value of a healthy lifestyle and a conduct of life of students was observed. Research has shown the high importance of occupations by physical culture and sport. The way of increase of popularity of tourism as sport is offered. Are given a work experience of section of sports tourism. Conclusion. The received results indicate the need of enhancement of methodology of teaching ecological bases of the higher school taking into account gender features of students.

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The first clinical experience of nanostructured propolis usage in treatment of patients with microbial eczema

Year: 2016, volume 12 Issue: №3 Pages: 500-504
Heading: Dermatovenerology Article type: Case report
Authors: Schnaider D.A., Utz S.R., Zayarskiy D.A., Gus'kova O.P., Gorokhovskiy A.V.
Organization: Saratov State Agrarian University named after N.I. Vavilov, Saratov State Medical University
Summary:

One of the most common forms of eczema is microbial eczema constituting 12-27% of all the cases of eczema. Application of nanotechnology in the field of medicine, including dermatology and cosmetology continues to increase. An example of innovation, demonstrating the results of research within the chemical technology and practical dermatology and cosmetology is a cosmetic product based on nanostructured systems "core — shell", which is an aqueous dispersion of nanoscale flavonoid "cores", derived from natural propolis which are stabilized by polyelectrolyte "shell". The purpose of this work is to conduct primary research on cosmetic product "Mellisol" on the basis of composite structures "core — shell" stabilized by polyelectrolyte membrane, for its application in the complex therapy in the treatment of microbial eczema. Description of these cases under clinical observation shows high efficacy and safety of cosmetic product "Mellisol" in the treatment of patients with microbial eczema in its acute phase.

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Innovative technologies of teaching self-government atopic dermatitis

Year: 2016, volume 12 Issue: №3 Pages: 495-497
Heading: Dermatovenerology Article type: Author's opinion
Authors: Utz S.R., Eremina M.G., Dolinina O.N.
Organization: Saratov State Agrarian University named after N.I. Vavilov, Saratov State Medical University
Summary:

The new understanding of the disease requires the development of modern methods in the management strategy of atopic dermatitis. Individual approach to educate patients with use of modern gadgets in addition to the standard methods of treatment is a relatively new concept in dermatology. Educational programs for atopic dermatitis have a positive impact on the severity of dermatoses, as well as on psychological status.

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Optimization of the technological cycle of formation of "core — shell" structures and the study of an- timicrobial and regenerative properties of the dispersions based on the prepared structures

Year: 2016, volume 12 Issue: №3 Pages: 462-467
Heading: Dermatovenerology Article type: Original article
Authors: Zayarskiy D.A., Gorokhovskiy A.V., Nechaeva O.V., Ul'yanov V.Yu., Tikhomirova E.l., Vakaraeva M.M., Schnaider D.A., Utz S.R., Arsenievich D.M.
Organization: Chechen State University, National Research Nuclear University "МЕРЫ", Saratov State Agrarian University named after N.I. Vavilov, Saratov State Medical University, SEH «Saratov regional dermatovenerologic dispensary»
Summary:

The aim of the work was to create optimized composite structures on the basis of nanoscale aggregates of fla-vonoids and study of their antimicrobial and regenerative properties. Material and methods. Antimicrobial activity of the resulting preparation was studied using the serial dilution method. Standard and clinical strains of Gram-positive and Gram-negative bacteria and microscopic fungi were used as experimental models. Assessment of regenerative effect of structures containing nanoaggregates flavonoids on experimental models of full thickness skin wounds was performed. Results. The high antimicrobial activity of the created structures is seen against opportunistic pathogenic microorganisms including clinical isolates resistant to multiple antibiotics. Displaying the reliable increase in rate of healing of experimental full thickness skin wounds by stimulating regenerative processes. Conclusion. Developed preparation containing "core — shell" structure stabilized by polyelectrolyte based flavonoid nanoaggregates can be considered as a potentially new type of drugs for use in cosmetology and dermatology as well as in the treatment of contaminated surgerical wounds and thermal injuries.

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Comparative evaluation of clarifying agents to improve the quality of the far long-wave ultraviolet therapy chronic dermatosis

Year: 2016, volume 12 Issue: №3 Pages: 453-458
Heading: Dermatovenerology Article type: Original article
Authors: Artemina Е.М., Utz S.R., Yuvchenko S.A., Zimnyakov D.A., Alonova M.V.
Organization: Saratov State Agrarian University named after N.I. Vavilov, Saratov State Medical University
Summary:

Objective; to choose the optical clearing agent with the best illuminating ability in the long-wave UV spectrum used in phototherapy. Material and methods. Ex vivo skin samples were used as objects of study. Measurement of the total transmission spectra of the skin sections was carried out on a multi-channel spectrometer Ocean Optics QE 65000 (Ocean Optics, USA) using 4 optical clearing agents (40% glucose solution, glycerol, propylene glycol, oleic acid).
Results. Having conducted a comparative analysis of ex vivo data collected from spectroscopy of these optical clearing agents at a wavelength of 370 nm, it was found that the maximum optical clearing was achieved using propylene glycol at 44 minutes, which was 11.56%. Conclusion. The use of optical clearing agents is possible not only to improve the visualization of the skin structure, but also to explore the dynamics of light transmission in long-wave UV A-1 therapy of patients.

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Problems and ways to improve the laboratory diagnosis of chlamydial infection

Summary:

The review highlights the historical aspects and modern concepts of laboratory diagnosis of chlamydial infection. The studies on investigation of different strains of Chlamydia trachomatis performed in Russian Federation and abroad are summarized. The results of research of domestic and foreign scientists aimed at finding the perfect laboratory test for identification of C. trachomatis on the basis of molecular biological methods are analyzed and presented.

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Detection of Chlamydia trachomatis in blood samples as a diagnostic method for complicated and persistent forms of urogenital chlamydia infections

Summary:

Goal: the study of the effectiveness of the method for laboratory diagnostics of urogenital chlamydial infection in patients with chronic form of the disease. Material and methods. The presence of DNAof C. trachomatis was detected by PCR in either genital or extragenital (blood) sites in eighth patients (four men and four women). Results. It is established that in biological material taken from extragenital (blood) sites, C. trachomatis was detected in all patients examined (in 100% of cases), while in clinical samples obtained from genital sites, in seven patients only (87.5%). Conclusion. We found that specific chlamydial DNAcan be detected in extragenital (blood) site, despite the negative reaction in the clinical material from the genital tract of patients with genital chlamydial infection.

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