Saratov JOURNAL of Medical and Scientific Research

Grodno State Medical University

Features of the prevalence of injecting drug use in the Republic of Belarus

Year: 2016, volume 12 Issue: №1 Pages: 7-11
Heading: Health Service Organization Article type: Original article
Authors: Lelevich V.V., Vinitskaya A.G., Sarana Y.V., Tishchenko E.M.
Organization: Grodno State Medical University
Summary:

Aim: to analyze the situation with injecting drug use in the Republic of Belarus during the period 2000-2014. Material and Methods. The analysis of the official data on the psychoactive substances' abusers, listed in the Narcological Register of the Ministry of Health in 2000-2014. Results. Over last 15 years the number of registered drug abusers increased three times, whereas the number of injecting drug users (IDUs) increased 2,2 times. The majority of recorded IDUs abused opium-based drugs and only 3% of them injected amphetamine-type stimulants. The increase in the number of recorded persons, who abuse synthetic opioids and analogues of well-known drugs, was noted during the last ten years. Conclusion. The data obtained indicate necessity of the studies on IDUs, and might be useful for working up preventive measures to restrain the spread of drug addiction.

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Regional anesthetic activity of new decahydroquinolinyl derivative by the experimental model of terminal anesthesia

Year: 2014, volume 10 Issue: №3 Pages: 384-389
Heading: Parmacology Article type: Original article
Authors: Goncharuk V.V., Buben A.L., Vdovichenko V.P.
Organization: Grodno State Medical University
Summary:

anesthesia. Material and Methods. Decahydroquinolinyl derivative under laboratory code PAS-68 synthesized in the A. B. Bekturov Institute of Chemical Sciences under the guidance of K. D. Praliev has been studied. Benzocaine, lido-caine and tetracaine were used as the comparison drugs. Male rabbits of 2,0-3,5 kg weight were used as experimental animals. A threshold of corneal sensitivity to tactile effects (Rainier index) was determined by the standard method. Computer prognosis of PAS-68 acute toxicity also was made. Results. The local anesthetic activity of 1 %, 0,5% and 0,25% solutions of PAS-68 were identified as higher than that for lidocaine and benzocaine in similar concentrations (p

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