Saratov JOURNAL of Medical and Scientific Research

Sheino I.N.

State Scientific Research Center n.a. A. I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency, Head of Laboratory of developing new methods of radiation therapy, Candidate of Physics and Mathematical Sciences

Rare earth elements in nuclear medicine

Year: 2014, volume 10 Issue: №4 Pages: 848-859
Heading: radiation medicine Article type: Review
Authors: Kodina G.E., Kulakov V.N., Sheino I.N.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

The review focuses on the key applications of stable and radioactive isotopes of rare earth elements in the technology of nuclear medicine, radionuclide diagnostics and therapy, as well as magnetic resonance imaging and binary radiotherapy technologies.

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Background of photon-capture therapy principle of malignant cancer treatment

Year: 2013, volume 9 Issue: №4 Pages: 878-881
Heading: Oncology Article type: Original article
Authors: Sheino I.N., Izhevskij P. W., Lipengolts A.A.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

Aim: the study of the physical effect of the local dose increasing in biological tissue at the gadolinium-containing drug under the influence of X-ray radiation. Material and Methods. Experimental and three independent numerical methods are obtained distribution of the absorbed dose in tissue-equivalent phantom containing a model of the tumor with a given concentration of gadolinium. Results. The presence of a gadolinium-containing drug in the biological tissue (1% Gd by weight) leads to a local increase of an absorbed dose up to 2 times under the influence of X-ray radiation. The difference in the results obtained calculated and experimental methods does not exceed 12%. Conclusion. The results of the study confirmed the basic theoretical background photon capture therapy, as well as the legal use of methods of mathematic modeling of the process of forming radiation in biological tissue, necessary for dosimetric photon capture therapy planning.

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