Saratov JOURNAL of Medical and Scientific Research

State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency

Physical factors impact on the status of regional hemodynamics and processes of microcirculation in patients with chronic bacterial prostatitis

Year: 2017, volume 13 Issue: №3 Pages: 537-540
Heading: Urology Article type: Original article
Authors: Samoylov A.S., Kulchitskaya D.B., Kolbakhova S.N., Goloborodko E.M., Bokov A.l., Konchugova T.V., Kiyatkin V.A.
Organization: Russian Scientific Center for Medical Rehabilitation and Balneology, State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

The goal of the research is to study the impact of vacuum interference therapy on the state of the regional hemodynamics and the processes of microcirculation among patients with chronic bacterial prostatitis. Material and Meth- ods. The study included 90 patients with average age 32.5 years with chronic bacterial prostatitis in a latent phase of inflammation. The study was conducted on a comparative basis using three randomized groups of patients (n=30), comparable on all criteria, divided depending on the methods applied into two treatment groups and one control group. Besides, the originally assigned basic medication treatment was an obligatory component in all three groups. Results. After therapy course the more significant results in hemodynamic changes were shown in the group of patients who received vacuum-interference therapy. The second group, which received interference currents, there was also positive dynamics in the hemodynamic parameters, but to a smaller extent, while in the control group there were no vivid changes found in the studied parameters. Conclusion. The course treatment using vacuum interference therapy among patients with chronic bacterial prostatitis had a significant positive corrective effect on the system of hemodynamics.

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Special cooling liquid and its practical application in sport medicine

Year: 2016, volume 12 Issue: №4 Pages: 721-726
Heading: sports medicine Article type: Review
Authors: Rasinkin S.M. Petrova V.V., Konovalov D.P., Bragin M.A.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency, Ltd. "MontClinic"
Summary:

The purpose of this study is to explore special cooling liquid in sports. We can predict the decrease in body temperature, reducing dehydration and increasing endurance using this liquid. Finally, special cooling liquid improves physical activity at high temperatures.

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Transarterial chemoembolization for primary and metastatic liver tumors

Year: 2016, volume 12 Issue: №4 Pages: 716-720
Heading: Oncology Article type: Review
Authors: Popov M.V., Aronov M.S., Voskanyan S.E., Karpova O.V.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

The literature review presents the methodology of transarterial chemoembolization (TACE) — widely used method of treatment of primary and secondary liver tumors. The TACE role as a neoadjuvant therapy and the role in the management of unresectable primary and secondary liver tumors are shown. The morphofunctional basis of TACE, benefits of superselective intra-arterial administration of cytostatic agents especially in combination with ischemic impact on a tumor are described. The subject of the choice of the chemotherapeutic agent is also touched; modern drug-loaded microspheres which allow the use of higher doses of the chemotherapeutic drug without increasing systemic effect and prolong its effect on tumor are described. Lack of correlation of presence and severity of a post-embolization syndrome with success of the procedure is noted.

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Role of a preoperative distal and proximal embolization of the right branch of the portal vein at surgical treatment of a liver malignant tumors

Year: 2016, volume 12 Issue: №4 Pages: 713-716
Heading: Oncology Article type: Original article
Authors: Popov M.V., Voskanyan S.E., Aronov M.S., Karpova O.V.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

Objective: assessment of safety and efficiency of application of the method of the distal and proximal embolization of the right branch of a portal vein using an occluder for preventive increase of the small future remaining liver amount in case of the planned resection. Material and methods. In the Burnazyan Federal Medical Biophysical Center that method was used in two cases: metastasises of bladder cancer in one case and of colorectal cancer in second case. Patients were males aged 57 and 64. Measuring the amount of future remaining liver volume was carried out with the CT-volumetry. Portal vein embolization of the right branch was carried out by transhepatic ipsilateral access using polyvinyl alcohol particles and occluder AVP II. Results. As a result in both cases the gain (9 and 24%), sufficient for performance of a resection, of the remaining liver volume was noted; the progression of the tumor process and periop-erative complications were not observed. Conclusion. Distal and proximal preoperative portal vein embolization is an effective and promising method, allowing surgeons to increase the number of operable patients and reduce the risk of postoperative liver failure.

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Pain syndrome features in Parkinson's disease

Year: 2016, volume 12 Issue: №4 Pages: 706-712
Heading: Neurology Article type: Review
Authors: Bril Е.М., Udalov U.D., Anikina M.A., Zimnyakova O.S.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

Pain in Parkinson disease take the special place among all of disease symptoms due to it pathogenetics and clinical diversity. In spite of the plurality of resent studies, the majority of clinical practioners and neurologists didn't pay attention to significant decline of the quality of life in patients with Parkinson disease and pain disorders. This article was created with aim to summarize all important results of studies, focused on pain pathogenesis and clinical features on different stages of disease.

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Computer tomography in the diagnosis of leiomyosarcoma of an inferior vena cava (case report)

Year: 2016, volume 12 Issue: №4 Pages: 702-705
Heading: Radiology Article type: Case report
Authors: Shikunov D.A., Bashkov A.N., Voskanyan S.E., Naidenov E.M., Grigorieva O.O., Orekhova N.V., Zabelin M.V.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

The review considered a rare case of leiomyosarcoma of the inferior vena cava, multiphase protocol disclosed value of multislice computed tomography for evaluation of tumor resectability

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Antistress activation therapy for cardiovascular diseases

Year: 2016, volume 12 Issue: №4 Pages: 696-701
Heading: Cardiology Article type:
Authors: Miroshnik E.V., Yeliseyeva N.A.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

The cohort pilot study had been done. Aim: to study the effectiveness of an antistress activation therapy on the functional state of human with the purpose of formation of adaptive reactions of activation and training high levels of reactivity among the two groups of patients with cardiovascular problems, ranks first among causes of death population: arterial hypertension (AH) and coronary heart disease (CHD). Material and methods. From the sub-sample of the Moscow population (396) were allocated to 2 groups of patients of 30 people in each (a control group and a group for anti-stress therapy for persons with hypertension and coronary artery disease that within 1 month took adaptogens (tincture of ginseng, Eleutherococcus, etc.) is minimized by a specially developed algorithm. For stress diagnosis international integrated questionnaire Perceived Stress (PSS); as well as Hospital Anxiety and Depression Scale (HADS) were used. Blood pressure, heart rate, body mass index, waist circumference were measured. In addition we used new methods "Antistress activation health improvement". Results. The average age in the intervention group was 59.4 years, and in the control group was 58.3 years, p>0.05. In compliance with results of the study has been marked that persons who were treated by methods "Antistress activation health improvement" sensed general and "internal" dumping, improving of duration and quality of sleeping. Irritability, level of stress, depression, and fatigability became rather less. Dynamics of emotions locked in psychometric scales showed distinct improvement of mood, decrease of fear, sorrow, anxiety, anger, emotional instability, increase of self-reliance, activity. Conclusion. The treatment of stress, anxiety, and depression must be complexes based on biological and psychological approaches.

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Microgliocyte argentation on histological sections of hippocampus of rabbits

Summary:

Purpose: to obtain morphological data to identify microglia on histological sections of hippocampus of rabbits using silver salt impregnation. Material and methods. Histological sections of hippocampus of rabbits impregnated with salt deposited silver. Using the Rio Hortega method for detecting fibrous glia, choose the desired chemical composition and acid-base parameters of the silver solution and reducing agent for the detection of microglia. Results. In histological sections of the hippocampus revealed microglia contrast with branched spikes and cells without shoots with thin flagellums. Conclusion. In visiting the experiments carried out in natural conditions, it is crucial to conduct biomedical research in the shortest possible time. We need to get not only the functional results of research, but also by their morphological, substantiating the data. The present method of impregnation microglia can be used as a rapid method for the morphological study of cerebral blood flow and neural tissue hypoxia.

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Use of a remote infrared thermography in experimental medicine at extreme influences

Summary:

The study presents an analysis of published data on the use of remote infrared thermography in medicine and veterinary science and evaluated the main opportunities, methods and ways of thermovision registration in experimental medical studies on biological objects, including at extreme influences. The following resources of the bibliographic electronic databases had been used: eLibrary, PubMed, Clinical Key, Science. Now methods of infrared thermography in insufficient degree are used in experimental medicine, including when studying adverse biological effect of various harmful and dangerous extreme factors, which main manifestation, especially in the early period after exposure, are systemic microvascular disorders, determining the state of capacity of human biomodels. These dynamic remote ther-mographic studies of experimental biological objects can be used to evaluate disorders of the peripheral circulation, working capacity and an emotional condition of the biomodels exposed to extreme factors, including early after experimental studies in laboratory and field work.

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Risk of cataract in the context of acute and chronic exposure

Year: 2016, volume 12 Issue: №4 Pages: 678-684
Heading: radiation medicine Article type: Original article
Authors: Tukov A.R., Shafransky I.L., Kapitonova N.V., Prokhorova O.N., Samoilov A.S.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:

Purpose: estimation of the risk of cataract using doses of different types of radiation. Material and methods. The study is carried out using the information database of the NP, recovery workers of the accident at the Chernobyl NP. Professional exposure and dose received during 30 km zone were used to calculate the risk. Results. The study shows the use of one of their parts of the total radiation dose of man, leads to obtaining of different levels of the risk of disease. Conclusion. Only use of a total radiation dose can lead to obtaining of the correct results of evaluating the risk of the emergence of the radiation- induced diseases.

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