Saratov JOURNAL of Medical and Scientific Research

SEH «Saratov regional dermatovenerologic dispensary»

Оценка затрат на лечение пациентов с разными формами псориаза в условиях круглосуточного стационара

Year: 2017, volume 13 Issue: №3 Pages: 612-616
Heading: Dermatovenerology Article type: Original article
Authors: Shnaider D.A., Utz S.R., Zayarskiy D.A., Nechaeva O.V., Guskova O.P.
Organization: Saratov State Medical University, Saratov State Technical University n.a. Yu.A. Gagarin, SEH «Saratov regional dermatovenerologic dispensary»
Summary:

Aim: preliminary studies have made it possible to establish for the polymer a broad spectrum of antimicrobial activity and to attribute it to low-toxic compounds. Material and Methods, the paper presents a comparative evaluation of the treatment of mild and moderate acne with the standard preparation adapalen+clindamycin and cosmetic product Mellisol to change the indices of the dermatological acne index (DAI). Results. The use of the cosmetic product "Mel-lisol" contributed to a significant reduction in the indices of CFU of bacteria. Conclusions. Using of the cosmetic product "Mellisol" is effective in the treatment of acne and showed its high efficacy and safety in the treatment of patients with mild and moderate acne.

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Optimization of the technological cycle of formation of "core — shell" structures and the study of an- timicrobial and regenerative properties of the dispersions based on the prepared structures

Year: 2016, volume 12 Issue: №3 Pages: 462-467
Heading: Dermatovenerology Article type: Original article
Authors: Zayarskiy D.A., Gorokhovskiy A.V., Nechaeva O.V., Ul'yanov V.Yu., Tikhomirova E.l., Vakaraeva M.M., Schnaider D.A., Utz S.R., Arsenievich D.M.
Organization: Chechen State University, National Research Nuclear University "МЕРЫ", Saratov State Agrarian University named after N.I. Vavilov, Saratov State Medical University, SEH «Saratov regional dermatovenerologic dispensary»
Summary:

The aim of the work was to create optimized composite structures on the basis of nanoscale aggregates of fla-vonoids and study of their antimicrobial and regenerative properties. Material and methods. Antimicrobial activity of the resulting preparation was studied using the serial dilution method. Standard and clinical strains of Gram-positive and Gram-negative bacteria and microscopic fungi were used as experimental models. Assessment of regenerative effect of structures containing nanoaggregates flavonoids on experimental models of full thickness skin wounds was performed. Results. The high antimicrobial activity of the created structures is seen against opportunistic pathogenic microorganisms including clinical isolates resistant to multiple antibiotics. Displaying the reliable increase in rate of healing of experimental full thickness skin wounds by stimulating regenerative processes. Conclusion. Developed preparation containing "core — shell" structure stabilized by polyelectrolyte based flavonoid nanoaggregates can be considered as a potentially new type of drugs for use in cosmetology and dermatology as well as in the treatment of contaminated surgerical wounds and thermal injuries.

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The role of motivational factors which make interns choose specialty of dermatovenerologist

Year: 2015, volume 11 Issue: №3 Pages: 476-479
Heading: Dermatovenerology Article type: Short message
Authors: Filonova A.V., Utz S.R., Schneider D.A., Igonina I.A.
Organization: Saratov State Medical University, SEH «Saratov regional dermatovenerologic dispensary»
Summary:

Objective: to analyze the main motivational and psychological factors influencing the success of the process of becoming a young medical interns in the specialty «Dermatovenereology». Materials and methods. The study involved 49 interns in the specialty «Dermatovenereology» (22 people studied in 2013-2014, 27 people — in 2014-2015). For the diagnosis it was used a Shortened multi-factor Personality inventory (RESINS), the technique of "career Anchors" diagnostic value orientations in karyes-re (E. Shane, translation and adaptation of V.A. Chiker, V. E. Vinokurov), «Survey of young specialists-sheet» developed by GUZ «SACVD» Results: A greater number of doctors interns of 2013 and 2014 and 2014-2015 chose the specialty «Dermatovenerology» because of the possibility to work in the field of cosmetology. Conclusions. These results provide the possibility of selecting candidates for future employment, identify motivate innovative features, the ability of young professionals.

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Psychocorrection activities in complex therapy of patients with psoriasis

Year: 2015, volume 11 Issue: №3 Pages: 466-471
Heading: Dermatovenerology Article type: Short message
Authors: Filonova A.V., Utz S.R., Schneider D.A., Guskova O.P.
Organization: SEH «Saratov regional dermatovenerologic dispensary», Saratov State Medical University
Summary:

Aim: to examine the psycho-emotional state of patients with psoriasis and to choose the optimal methods of correctional interventions with patients and their family-relatives. Materials and methods. The study included 230 patients with various different forms of psoriasis (150 men and 80 women, mean age 42±2,3) and 183 of their cohabitating relatives. The method of С D. Spielberg and J. L. Khanin was used for the assessment of anxiety degree, quality of life assessment (SF-36 health status survey), as well as a questionnaire, elaborated by our team, for patients with psoriasis. Results. After psychocorrection events in the patients there were noticed the following: decreased anxiety, increased vitality, improved relationships with loved ones, improved emotional state. Conclusion. When using psychotherapy in combination with medication, psoriasis treatment becomes more effective: reduced levels of anxiety, increased life activity, interaction with loved ones becomes more confident, improves emotional state.

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Diagnostic value of dermatoscopy in case of psoriasis

Year: 2015, volume 11 Issue: №3 Pages: 462-466
Heading: Dermatovenerology Article type: Short message
Authors: Utz S.R., Sherstobitova K.Y., Schneider D.A.
Organization: Saratov State Medical University, SEH «Saratov regional dermatovenerologic dispensary»
Summary:

Aim: to evaluate the picture of dermatoscopy in case of psoriasis at different stages of the disease. Materials and Methods. We observed 30 patients with a diagnosis of disseminated papular — plaque psoriasis at the stage of progression. Dermatoscopic study was conducted by the expert class videodermatoskop MoleMaxHD (company Derma Medical Systems, Austria), with an increase from x30 to x80 to initiation of therapy, on the 7th and 15th days of treatment. Results. Changes of dermatoscopic picture in psoriasis are observed on the first days of treatment, and outperformed the major clinical manifestations of infections detected by the human eye. Conclusion. Dermatoscopy reveals the earliest signs of positive dynamics of the therapy and can be used to select a rational method of treatment.

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The combination of psoriasis and secondary syphilis. Role of dermatoscopy in differential diagnostics

Year: 2015, volume 11 Issue: №3 Pages: 447-450
Heading: Dermatovenerology Article type: Case report
Authors: Sherstobitova K.Yu., Schnaider D.A., Utz S.R.
Organization: Saratov State Medical University, SEH «Saratov regional dermatovenerologic dispensary»
Summary:

A clinical case of the combination of psoriasis and secondary syphilis is presented. The problem of differential diagnostics of the clinical manifestations of syphilis and psoriasis, including the dermatoscopy usage are considered.

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Clinical case of Hailey-Hailey disease

Year: 2015, volume 11 Issue: №3 Pages: 442-444
Heading: Dermatovenerology Article type: Short message
Authors: Karpova E.N., Schneider D.A., Bobko N.K.
Organization: SEH «Saratov regional dermatovenerologic dispensary»
Summary:

The study presents a relatively rare case of dermatosis. It is familial benign chronic vesicular fever (Hailey-Hailey disease) in a 58-years old female patient which is inherited as an autosomal dominant mode. The data about etiology, pathogenesis, clinical picture and differential diagnosis were summarized. The main ways of treatment of the disease are described.

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Clinical features of mastocytosis in children

Year: 2015, volume 11 Issue: №3 Pages: 439-441
Heading: Dermatovenerology Article type: Case report
Authors: Shustova О.А., Schnaider D.A., Morrison A.V., Sherstobitova K.Y.
Organization: Saratov State Medical University, SEH «Saratov regional dermatovenerologic dispensary»
Summary:

A case of cutaneous mastocytosis, relating to the rarely seen dermatoses, is presented in the study. The data of etiology, pathogenesis, clinical picture are generalize.

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Legal aspects of medical care for patients with neoplasms of skin in institutions of dermatovenerologic profile

Year: 2014, volume 10 Issue: №3 Pages: 574-576
Heading: Skin Diseases Article type: Author's opinion
Authors: Sherstobitova K.Y., Schnaider D.A.
Organization: SEH «Saratov regional dermatovenerologic dispensary»
Summary:

There is a model of care for patients with neoplasms of the skin in the institutions of dermatovenerologic profile with the existing legal documents. Example: Saratov regional dermatovenerologic dispensary.

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Method of correction of early and long-existing hypertrophic scars and keloids

Year: 2014, volume 10 Issue: №3 Pages: 558-560
Heading: Skin Diseases Article type: Short message
Authors: Shnaider D.A., Drobysheva К.О.
Organization: SEH «Saratov regional dermatovenerologic dispensary»
Summary:

Aim: то assess the effectiveness of the combined method for the correction of early and long-existing hypertrophic scars and keloids by intrascar injection of "Longidaza ME" medication and phonophoresis. Material and methods. A combined method of correction of hypertrophic scars and keloids, comprising the introduction of the "Longidaza ME" by intrascar injection and using phonophoresis. Results. Evaluation of the results was determined based on indicators of dermatology quality of life index. When comparing long-term results positive result was noted in 90% of cases. Conclusion. The study confirmed the effectiveness of the combined method in preventing reactive growth of connective tissue and ability to cause regression of fibrosis, i.e. to correct a complex autoregulatory reactions of connective tissue, which is clinically expressed in resorption and deposition of scar.

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