Macro- and Micromorphology
Characteristics of Clinico-pathologic Presentations of Chronic Gastroduodenitis in Children with Lambliasis Invasion
Heading: Macro- and Micromorphology Article type: Original article
Authors: Matveeva O.V., Maslyakova G.N., Zhandarova L.F., Popova I.Yu., Neklyudov Yu.A., Alekseev Yu.D.
Organization: Saratov State Medical University
The analysis of anamnestic and clinical indices, and also morphological investigation of biopsy materials of mucous coat of stomach and duodenum in children with chronic gastroduodenitis of different etiology including lambliasis invasion is carried out with the purpose of detecting features of clinicopathologic presentations of chronic gastroduodenitis in children with and without lambliasis invasion. Material and methods. 100 patients (50 children with confirmed lambliasis invasion and 50 patients without lambliasis invasion) aged from 2 up to 16 were under observation. The material for histologic study was received as a result of fibrogastroduodenoscopy carried out with target biopsy of fundic, antrum and duodenum mucosa. Results. As a result of the findings moderate pains sited in epigastric and periumbilical regions are characteristic for children with lambliasis invasion; irradiation and cramping characteristics of pains are typical. Conclusion. Manifestation of pains is not connected with the time of day and food intake, manifestation of seasonal prevalence is not typical as well, and progression of inflammatory process in the mucous coat of the stomach and duodenum is declared itself as a diffuse gastritis of the fundic part, a diffuse gastritis of the antral part, subatrophic duodenitis with cyst formation of Brunner's glands, and also the presence of eosinophilic leucocytes in the cellular infiltrate
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| 201201_016-022_.pdf | 2.45 MB |
Comparative analysis of morphogeometric parameters of forward cranial pole depending on type of a skull basis
Heading: Macro- and Micromorphology Article type: Original article
Authors: Aleshkina О.Yu., Hurchak Yu.A., Rossoshansky D.N., Anisimov A.N.
Organization: Saratov State Medical University
The purpose of the work is comparison of parameters of a forward cranial pole depending on type of a skull basis. The research material contained 100 adult skulls divided into three craniotypes. The method of craniotopometry was used for measuring the parameters and further calculation of average value and their comparison among themselves. Results. The research helped to reveal that length of a forward cranial pole, length of a lateral part on the right and at the left, a corner f.c.-s-n prevail at flexibasilar craniotype. Conclusions. The width of a forward cranial pole, width of a lateral part on the right and at the left, a corner f.c.-n-g are more at platibasilar craniotype
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| 201201_014-016_.pdf | 249.73 KB |
Morphological and biomechanical structural characteristics of medial cerebral artery in adults
Heading: Macro- and Micromorphology Article type: Original article
Authors: Nikolenko V.N., Fomkina О.A., Nekljudov Ju.A., Alekseev Ju.D.
Organization: Saratov State Medical University
The research goal is to study general strength, breaking point, Young's modulus (tensile modulus), absolute and relative strain of medial cerebral artery. Materials end methods. External diameter of medial cerebral artery, thickness of its wall and diameter of a lumen have been measured under the microscope on cross-section edges. In total 200 arteries (144 — from corpses of men, 56 — from corpses of women) received not later than 16 hours after autopsy of adults have been investigated. Results. Lethal cases resulted from acute or chronic vascular cerebral pathology have not been included in the study. Authentic predominance of wall thickness (14,8%), lumen diameter (50,3%) and general wall strength (13,8%) has been revealed statistically in men. Bilateral differences of parameters have been expressed by 1,0% (external diameter and wall thickness of an artery) to 10,0% (Young's modulus) and have been determined as statistically insignificant (p>0,05). Age aspect has shown intensity of morphological characteristics of medial cerebral artery. In conclusion it is worth while noting that after the age of 35 wall strength and resistance to strain of medial cerebral artery are authentically diminished; the artery becomes less rigid. Capability to elongation remains constant but after the age of 75 it decreases
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| 201201_009-014__.pdf | 407.78 KB |
Pathological and morphological features of bladder neck sclerosis
Heading: Macro- and Micromorphology Article type: Original article
Authors: Nashivochnikova N.A., Krupin V.N., Klochay V.V., Artifeksova A.A.
Organization: N. Novgorod State Medical Academy
The research goal is to estimate a condition of microcirculation in a bladder neck in patients with benign prostatic hyperplasia (BPH) and its value in pathogenesis of bladder neck sclerosis. Materials and methods: Work basis included the analysis of treatment results of 1171 patients with BPH who carried complex examination, operative treatment and further supervision. The basic group was made up of 182 patients with BPH who developed bladder neck sclerosis in the postoperative period. The control group consisted of 200patients with BPH who did not develop the described pathology. clinico-anamnestic, laboratory methods and instrumental studies were used. Results: Disturbance of microcirculation in a bladder neck was considered to be a pathogenetic factor of sclerosis development as one of seri¬ous complications of operative treatment in case of BPH. The presence of microcirculatory disorders was confirmed by histological analysis. Inflammation in the bladder neck should be considered as an aggravating factor. Conclusion: The presence of microcirculatory disorders in the bladder neck in patients with BPH requires preoperative corrective therapy for prevention of sclerosis
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| 201104_768-771.pdf | 898.87 KB |
Clinicopathologic basis of hemodynamics modelling in the system of coronary arteries in consideration of its interaction with myocardium (review)
Heading: Macro- and Micromorphology Article type: Review
Authors: Chelnokova N.O., Golyadkina A.A., Schuchkina O.A.
Organization: Saratov State Medical University
The review presents the features of modern viewpoints on the theory of atherosclerosis pathogenesis. The possibilities of mathematical modelling of hemodynamics in coronary arteries in consideration of their morphological parameters and relationship with myocardium are described
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| 201104_762-768.pdf | 300.62 KB |
Morphological changes of internal organs and brain at prolonged oral administration of iron nanoparticles
Heading: Macro- and Micromorphology Article type: Short message
Authors: Navolokin N.A., Kun S.M.
Organization: Saratov State Medical University
Objective: Morphological changes of internal organs and brain of laboratory animals have been studied at prolonged oral administration of iron nanoparticles in experiments. Materials and methods: Iron nanoparticles 70±10 nm, 28 male white rats, and morphological methods of evaluation have been used in the experiment. Results: Studies have shown that the changes depend on nanoparticle concentration and signs of circulatory disorders and degenerative changes of parenchymatous elements
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| 201104_760-762.pdf | 260.79 KB |
Interrelationship of middle cranial fossa parameters and dimensional characteristics of human cerebral cranium in various craniotypes
Heading: Macro- and Micromorphology Article type: Original article
Authors: Aleshkina O.U., Anisimov A.N., Bukreeva E.G., Khurchak U.A.
Organization: Saratov State Medical University
The research goal is to study the interrelation between the linear dimensions of the middle cranial fossa, and linear and angular parameters of the human cerebral cranium depending on the basilar angle. Materials and methods: The research work has included 100 skulls of adults divided into three craniotypes. The craniotopometric method has taken into account parameters with further calculation of average values. correlation model has been formed. Results: The study of correlation characteristics of middle cranial fossa linear dimensions with cerebral cranium linear and angular parameters has shown different interrelation of craniotypes according to the strength and direction. Conclusion: It has been found out that a definite degree of interrelation has been observed in platibasilar craniotypes. Direct interrelation of middle cranial fossa length, length and width of sella turcica fracture has been observed in flexibasilar craniotypes. The interrelation of parameters studied in mediobasilar craniotypes has been determined in a lesser degree. Other dimension middle cranial fossa and sella turcica fracture are subjected to greater variability
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| 201104_757-760.pdf | 305.64 KB |
Obliteration of serrated sutures of a human skull (review)
Heading: Macro- and Micromorphology Article type: Review
Authors: Zaichenko A.A., Kochenkova О.V., Anisimova Е.А., Anisimov D.I., Lukin О.Yu.
Organization: Saratov State Socio-Economic University, Saratov State Medical University, Saratov Scientific Research Institute of Traumatology and Orthopedics
The review presents information on obliteration of serrated sutures of a human skull. It considers the age-specific variability and sexual dimorphism. The causes of craniostenosis and dependence of cranial form on degree and type of craniostenosis are described
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| 201103_567-572.pdf | 328.07 KB |
Complexity of serrated sutures of a human skull
Heading: Macro- and Micromorphology Article type: Original article
Authors: Kochenkova О.V., Zaichenko A.A., Anisimova Е.А., Anisimov D.I.
Organization: Saratov State Socio-Economic University, Saratov State Medical University, Saratov Scientific Research Institute of Traumatology and Orthopedics
Objective: to reveal the variability mechanism of complexity of serrated sutures of a human skull in the correlation with cranial form. Materials and methods. Researches of 253 arches of male and female skulls of patients at the age of 1 day-105 years without signs of cranial trauma or skeletal systemic diseases with absence of morphological signs of increase of intracranial pressure. Minimal (Min) and maximal (Max) values, average arithmetic (M), a mistake of average arithmetic (m) have been studied. For definition of reliability of average size difference parametrical and non-parametric statistical criteria were used: parametrical criterion (t-criterion of Student) applied for parameters submitting to the law of normal distribution (Lakin G. R, 1990). Distinctions of average arithmetic size were considered statistically authentic from 95% (p
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| 201103_563-567.pdf | 544.16 KB |
Morphological characteristics of sphincter zone glands of urinary bladder in different stages of postnatal ontogenesis
Heading: Macro- and Micromorphology Article type: Original article
Authors: Shadlinskiy V.B., Guseynova G.A., Mamedov N.M.
Organization: Azerbaijan Medical University
Methods of macromicroscopy and morphometry have been used to study sphincter zone glands by 54 total preparations of a urinary bladder received from corpses of people of different ages without any pathology of organs of urine-genital apparatus. The glands were painted by 0, 05% methylene blue solution and were investigated with the application of stereomicroscopic-binocular microscope MBS-9. Microscopic sections of sphincter zone glands in the thickness 5-7 microns were stained with hematoxylin-eosin, azure-2-eosin and with hematoxylin-picrofucsin by Van-Gizon technique. Sphincter zone glands are arranged firmly without dependence on age, length and width of initial department of glands of these zones. In postnatal ontogenesis size indices of sphincter zone glands have been essentially changed. These indices are equal for left and right ureter sphincter zone glands
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| 201102_357-361.pdf | 908.74 KB |

