Probability of developing severe sepsis in patients of elderly and senile age with necrotic erysipelas
Year: 2015, volume 11 Issue: №2 Pages: 198-201
Heading: Phthisiology Article type: Original article
Authors: Shapkin Yu.G., Khilgiyaev R.H., Mikhailenko K.A.
Organization: Saratov State Medical University
Heading: Phthisiology Article type: Original article
Authors: Shapkin Yu.G., Khilgiyaev R.H., Mikhailenko K.A.
Organization: Saratov State Medical University
Summary:
Objective: the probable determination of severe sepsis in patients of elderly and senile age with necrotic erysipelas based on a comprehensive assessment (clinical examination using systems — scales and determination of the level markers of SIRS). Material and methods. The analysis of peculiarities of necrotic erysipelas clinical course in 59 patients. The first group consisted of 17 patients with severe sepsis, the second — 18 patients with sepsis without multiple organ failure, in the comparison group —22 patients with local infection. We determined albumin, urea, creatinine, pro-calcitonin of plasma. The scale SAPS III was used to quantify SIRS, scale SOFA —to determine the extent of damage to organs and systems. Results. The most sensitive marker of developing sepsis in patients with necrotic erysipelas was procalcitonin. The second important indicator of SIRS severity in patients with necrotic erysipelas was the blood albumin. Scale SAPS III also allows to select a group of patients with high risk of developing severe sepsis. Use of the SOFA to predict the scale has been found out to be less important. Conclusion. A comprehensive assessment of the severity of the condition by scale SAPS III in combination with determining the levels of procalcitonin and plasma albumin is advisable to apply for prediction the probability of developing severe sepsis in patients of elderly and senile age with necrotic erysipelas. For the last indicator it is important to assess of absolute values and the decrease of its concentration.
Bibliography:
1. Eriksson В, Andersson G, Holm S, et al. Epidemiological clinical aspects of invasive group A streptococcus infections and the streptococcal toxic shock syndrome. Clin Inf Dis 1998; (27): 1428-1436
2. Danilova ТА. The invasive infections is caused by group A streptococcus and streptococcus toxic shock syndrome. Microbiology 2001; (3): 99-105
3. Olivier С. Severe Streptococcus pyogenes cutaneous infections. Arch Pediatr 2001; (4): 757-761
4. Gelfand BR, Yakovlev SV, Yarosheckyi Al, et al. The use of activated protein С in treatment of patients with severe sepsis. Surgery 2004; (1): 19-24
5. Adjamov ВМ, Shlyapnikov SA, Naser NR. Principles of patient-oriented antimicrobial therapy in the treatment of patients with septic complications. Infections in surgery 2011; (1): 26-30
6. Gelfand BR, Filimonov Ml, BraznikTB, etal. Procalcitonin: a new laboratory diagnostic marker of sepsis and septic complications in surgery (p. 1). Intensive care herald 2003; (1): 9-12
7. Meisner М, Tschaikowsky К, Palmaers Т, et al. Comparison of procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations at different SOFA scores during the course of sepsis and MODS. Critcal Care 1999; 3 (1): 45-50
8. Meisner M, Tschaikowsky K, Palmaers T, et al. Comparison of procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations at different APACHE II scores during the course of sepsis and MODS. Anaesthesiology (Abstract) 1997; (87): 243
9. Rodoman GV, Shalaeva Tl, Dinjinova TV. Albumin in the SIRS and multi organ insufficiency syndrome. Infections in surgery 2004; (3): 12-16.
| Attachment | Size |
|---|---|
| 2015_02_198-201.pdf | 354.72 KB |
Русский
English