Saratov JOURNAL of Medical and Scientific Research

Risk factors and progression of the left ventricular myocardial hypertrophy

Year: 2015, volume 11 Issue: №2 Pages: 141-145
Heading: Internal Diseases Article type:
Authors: Lazutkina A.Yu., Gorbunov V.V.
Organization: Chita Regional Directorate of Medical Supply on Trans-Baikal Railway, Chita State Medical Academy
Summary:

Tftea/mofthis workisto study the left ventricular myocardial hypertrophy. Materials and methods: In the study that was held in period from 2008 to 2013 years and covers group of 7959 workers of locomotive brigades of Transbaika-lian railway. In stated period each individual was additionally searched for the risk factors and lesions in target-organs in time of medical examinations undergoing. Results: During the study in group (7959 observations with the terminal outcomes) 597 cases of the left ventricular myocardial hypertrophy were found and statistically analyzed. It has been found that arterial hypertension, age, retinopathy, diabetes mellitus, thickening of the intima — media complex of more than 0.9 mm/atherosclerotic plaques of the carotid arteries, body mass index >25.0, and atherosclerosis of the aorta, hyperglycemia and stress led to the development of the left ventricular myocardial hypertrophy. Conclusions: This causative and effect conditionality should be considered in the prevention and treatment of the left ventricular myocardial hypertrophy.

Bibliography:
1. Lorell BH. Transition from hypertrophy to failure. Circulation 1997;96:3824-7
2. Molkentin JD, Olson EN. GATA4: a novel transcriptional regulator of cardiac hypertrophy? Circulation 1997; 96: 3833-5
3. Levy D, Garrison RJ, Savage DD, et al. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. N Engl J Med 1990; 322 (22): 1561-6
4. Koren M, Richard B, Devereux M, et al. Relation of left ventricular mass and geometry to morbidity and mortality in uncomplicated essential hypertension. Ann Intern Med 1991; 114: 345-52
5. Shherbakova AG. Remodeling of left ventricle at stage of chronic kidney disease. Vestnik sovremennoj klinicheskoj medici-ny 2010; 3 (1): 209-210
6. Levy Bl, et al. Coronary microvasculature alteration in hypertensive rats: effects of treatment with diuretic and an ACE inhibitor. Am J Hypertens 2001; 14: 7-13
7. Shherbakova ТА, Aleksandrova NL. Risk factors and left ventricular hypertrophies of patients with arterial hypertension in Saratov region. Bjulleten' medicinskih Internet konferencij 2013; 3 (2):133
8. Diagnosis and treatment of arterial hypertension: Recommendations RMSAH and RSSC. Kardiovaskuljarnaja terapija i profilaktika 2008; 7 (6): 1-32
9. The Russian medical society of hypertension. Diagnosis and treatment of hypertension: Rossijskie rekomendacii (4-j peresmotr). Sistemnye gipertenzii 2010; 3: 5-33
10. Schillaci G, Verdecchia Р, Porcellatti С, et al. Continuous relation between left ventricular mass and cardiovascular risk is essential hypertension. Hypertension 2000; 35: 580-6
11. Gottdienner JS, Reda DJ, Materson BJ, et al. Importance of obesity, race and age to the cardiac structural and functional effects of hypertension. J Am Coll Cardiol 1994; 24: 1492-8
12. Order №796 of Health Ministry "On approval of the list of medical contra-indications to work directly related to trains and shunting", http://base.consultant.ru
13. Klochkova ЕА. Labour Protection on railway transport: Textbook for technical schools and colleges. M., 2004; 412 p.
14. Cardiovascular prevention: Recommendations of RSSC. Kardiovaskuljarnaja terapija i profilaktika 2011; 10 (6): 1-64
15. Atkov OYu, ed. Ultrasound examination of heart and blood vessels. Ed. by M.: EKSMO, 2009; 400 p.
16. Poirier Р, Giles Т, Bray G, et al. Obesity and cardiovascular disease: pathophysiology, evaluation, and effects of weight loss: An update of the 1997 american heart association scientific statement on obesity and heart disease from the obesity committee of the council on nutrition, physical activity, and metabolism. Circulation 2006; 113: 898-918
17. Neves MF, Schiffrin EL, Aldosterone: a risk factor for vascular diseases. Cur Hypertens Rep 2003; 5: 59-65
18. Sato A, Saruta T, Aldosterone escape during angioten-sin-converting enzyme inhibitor therapy in essential hypertensive patients with left ventricular hypertrophy. J Intern Med Res 2001; 29: 13-21
19. Hameedi A, Shadow HL., The promise of selective aldosterone receptor antagonists for the treatment of Hypertension and Chronic Heart Failure. Cur Hypertens Rep 2000; 2: 378-83
20. Mychka VB, Gornostaev VV, Shikina NJu, Chazo-va IE. Hypertension and obesity. Cons med 2001; 2: 17-22
21. Kamm AJ, Luscher TF, Serruys PW. Diseases of heart and vessels. M.: GEOTAR-Media, 2011; 1211 p.
22. Shalimov РМ. Clinicopathological analysis of three cases of sudden cardiac death of young people. Kliniches-kaja medicina 2006; 10: 71-74
23. Guide postprandial hyperglycemia. International Diabetes Federation, 2007; 29 p.
24. Ripp TM, Mordovin VF. Peripheral progression markers of target-organ lesions of patients with hypertension. Sibir-skij medicinskij zhurnal 2008; 2: 126-127
25. Paraskevas Kl, Mikhailidis DP, Liapis CD. Internal carotid artery occlusion: association with atherosclerotic disease in other arterial beds and vascular risk factors. Angiology 2007; 58: 329-335
26. Park HW, Kim WH, Kim KH, et at. Carotid plaque is associated with increased cardiac mortality in patients with coronary artery disease. Int J Cardiol 2013; 166: 658-663
27. Barbarash OL, Zykov MV, Kashtalap VV, Barbarash LS. Prevalence and clinical significance of multifocal atherosclerosis in patients with ischemic heart disease. Kardiologiia 2011; 51: 66-71
28. Pipitone S, Corrado E, Muratori I, et al. Extracoronary atherosclerosis in patients with chronic ischemic heart disease: relationship with risk factors and the severity of coronary artery disease. Int Angiol 2007; 26: 346-352
29. Keo HH, Baumgartner I, HirschAT, etal. Carotid plaque and intima-media thickness and the incidence of ischemic events in patients with atherosclerotic vascular disease. Vase Med 2011; 16:323-330
30. Inaba Y, Chen JA, Bergmann SR. Carotid plaque, compared with carotid intima — media thickness, more accurately predicts coronary artery disease events: a meta-analysis. Atherosclerosis 2012; 220: 128-133
31. Sillesen H, Muntendam P, Adourian A, et al. Carotid plaque burden as a measure of subclinical atherosclerosis: comparison with other tests for subclinical arterial disease in the High Risk Plaque Biolmage study. JACC Cardiovasc Imaging 2012; 5: 681-689.

AttachmentSize
2015_02_141-145.pdf284.41 KB

No votes yet