Saratov JOURNAL of Medical and Scientific Research

Changes in the lipid composition of blood under the influence of a single submaximal exercise capacity (experimental research).

Year: 2015, volume 11 Issue: №2 Pages: 123-125
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Ermolaeva E.N.
Organization: South Ural State Medical University
Summary:

In acute physical exercise, there is a change in oxygen delivery working tissues, blood gas transport function and efficiency of the use of oxygen by cells in the process of metabolism, which is the basis for compensation for physical activities. Lipid metabolism plays an important role in the energy supply of muscle activity. The aim of our research is to study the effect of a single submaximal exercise capacity by changing the lipid profile of peripheral blood. Materials and Methods. The study was performed on 18 white rats. Model of acute exercise: animals swam 4 minutes with a load weighing 20% of body weight. Blood sampling was performed by intracardiac way, right after exercise. The blood lipid profile was determined. Results. In the experiment reported an increase in triglycerides, total cholesterol, very low-density lipoproteins, but the atherogenic ratio is maintained at the control values, due to a significant increase in the level of high-density lipoprotein. Conclusion. Acute submaximal exercise capacity by untrained body has an atherogenic effect. Working muscles during physical activity is a major consumer of free fatty acids, which are the source of atherogenic lipoprotein form of the very low and low density.

Bibliography:
1. Janssen I, Ross R. Linking age-related changes in skeletal muscle mass and composition with metabolism and disease. J Nutr Health Aging 2005; 9: 408-419
2. Kallman DA, Plato CC, Tobin JD. The role of muscle loss in the age-related decline of grip strength: cross-sectional and longitudinal perspectives. J Gerontol 1990; 45: 82-88
3. Kay SJ, Fiatarone Singh MA. The influence of physical activity on abdominal fat: a systematic review of the literature. Obes Rev 2006; 7: 183-200
4. Singh M. Exercise and aging. Clin Geriatr Med 2004; 20: 201-221
5. Pate R, Pratt M, Blair S, et al. Physical activity and public health. A recommendation from the Centers for Disease Control and Prevention and the American College of Sports Medicine. JAMA 1995; 273: 402-407
6. Kelley GA, Kelley KS. Aerobic exercise, lipids, and lipopro-teins in men: a meta-analysis of randomized controlled trials. J Mens Health Gend 2006; 3 (1): 61-70
7. Krasnov AF, Samodanova Gl, Usik SV, Yakovlev NN. The level of lactic acid in the blood as an indicator of response to exercise. Physiological Journal of the USSR named after IM Sechenova 1978; 64 (4): 538-542
8. Volkov Nl, Savelyev IA. Oxygen request and energy cost of intense muscular activity in man. Human Physiology 2002; 28 (4): 80-93
9. Knorre DG. Biological chemistry. Moscow: Nauka, 2002; 479 p.
10. Arai Y, Sasaki М, Sakuragawa N. Hypoxic effects on cholesterol metabolism of cultured rat aortic and brain microvas-cular endothelial cells, and aortic vascular smooth muscle cells. Tohoku J Exp Med 1996; 180: 17-25
11. Yonan T, Qiulin T. Inhibition of cholesterol biosynthesis under hypoxia. Submitted to the Office of Graduate Studies of Texas A&M University 2005; 1: 1-26.

AttachmentSize
2015_02_123-125.pdf311.44 KB

No votes yet