Saratov JOURNAL of Medical and Scientific Research

Content of vascular endothelial growth factor in blood serum and gastric juice in children with chronic inflammatory diseases of stomach and duodenum

Year: 2014, volume 10 Issue: №1 Pages: 110-113
Heading: Pediatrics Article type: Original article
Authors: Zavyalova O.V., Spivakovsky У.М., Zakharova N.B., Lukina O.A., Sirotkin E.A.
Organization: Saratov State Medical University
Summary:

The aim: to assess the levels of vascular endothelial growth factor (VEGF) in children with chronic inflammatory diseases of stomach and duodenum. Material and methods. 67 children with chronic inflammatory diseases of gastroduo-denal zone have been investigated. The substrate of the study included the serum and portion of gastric content. The data obtained were compared with a group of healthy children. Results. Maximum high content of VEGF was identified in children with duodenal ulcer. Conclusion. The content of this indicator depended on the Helicobacter pylori infection.

Bibliography:
1. Shcherbakov PS. Modern problems of teenage Gastroenterology. Pediatriya 2010; 89 (2): 6-17; 2. Baranskaya ЕК, Ivashkin VT, Sneptulin АА. Modern approaches to the treatment of peptic ulcer. In: Prevention and treatment of chronic diseases of the upper gastrointestinal tract. Moscow: MEDpress-inform, 2013; p.75-78; 3. Isakov VA, Domaradskiy IV. Helikobakterioz. Moscow: Medpraktika-M, 2003; 412 p.; 4. Stannard АК, Khurana R, Evans IM, et al. Vascular endothelial growth factor synergistically enhances induction of E-selectin by TNF-a. Arterioscler Thromb Vase Biol 2007; 27 (3): 494-502; 5. Ferrara N. Vascular endothelial growth factor. Arterioscler ThrombVasc Biol 2009; 29 (6): 789-791; 6. Gavrilenko Tl, Ryzhkova NA, Parkhomenko AN. Vascular endothelial growth factor in the clinic of internal medicine and its pathogenetic significance. Ukrainskiy kardiologicheskiy zhurnal 2011; (4): 87-95; 7. Kaplanskaya IB, Glasko EN, Frank GA. Angiogenesis, cell-cell contacts and stromal-parenchymal relationships in normal and pathological. Ros onkol zhurn 2005; (4): 53-57; 8. Islamova Е.А. Clinical features, diagnosis and treatment of gastric ulcer and duodenal ulcer in patients of different ages [dissertation]. Volgograd: Volgogradskiy Meditsinskiy Universitet, 2010; 9. Matveeva LV, Mosina LM, Novikova LV Changes in vascular endothelial growth factor in chronic atrophic gastritis. In: Sbornik tezisov 6 natsional'nogo Kongressa terapevtov. M., 2011; p. 269; 10. Merentsev SP, Lisnyak IA, Osinskiy DS, et al. Level of vascular endothelial growth factor in the serum of patients with gastric cancer. Onkologiya 2007; 9 (1): 21-24.

AttachmentSize
2014_01_110-113.pdf229.31 KB

No votes yet