2013, volume 9

The aim of the article is to present a review and analysis of historical data concerning theories of testicular movement and the role of gubernaculum in the process of descent. Comprehensive analysis of morphological data involving the anatomical and histological characteristics has been considered in the work. Key factors involved into the mechanisms of testicular movement and functional role of gubernaculum in this process have been described in details. Particular attention has been paid to neurohumoral regulation.

The aim of the article is to conduct analysis of accumulation and biodistribution of gold nanoparticles in the structural and functional areas of mesenteric lymph nodes of white rats. Particular attention is paid to the size and duration of oral administration. Material and Methods: Dark field microscopy with Leica DM 2500 microscope has been used to assess biodistribution of gold nanoparticle. The histochemical reaction of silver amplification with silver lactate by Danscher has been used to confirm gold nanoparticles identification. Results: It has been found that regardless of the duration of administration gold nanoparticles of 1-3 nm have not been detected by these methods in the lymph nodes. Gold nanoparticles of 15 and 50 nm have been found out in the form of clusters in the cytoplasm of macrophages and lymphocytes mainly in the mantle zone of lymphoid follicles and brain strands. Conclusion: It has been established that the gold nanoparticles of 15 and 50 nm has been detected in the form of clusters in the cytoplasm of macrophages and lymphocytes.

The purpose of the work is to define the location and the direction of nutrient canal of diaphysis and zone of concentration of nutrient foramina of shin bones. Material and methods: Parameters of tibia and fibula (n=208) of adults aged from 22 to 89 years (118 men and 90 women) have been studied. Results: The phenomena of individual and age variability, sexual dimorphism and bilateral dissymmetry of the position and the direction of nutrient canal and zones of concentration of nutrient foramina of tibia and fibula have been investigated. The distance of nutrient foramen at various types of shin bones has been defined. Conclusion: Position and direction of nutrient canal of diaphyses of shin bones differ in varioust bone types.

The purpose of the article is to present the main indicators of cancer morbidity and mortality in Nizhny Novgorod region in comparison with those in Russia in dynamics for the period of 10 years. The survey outlines the necessity of regional palliative care development. It has been revealed that the organization of specialized palliative care centers on the basis of Oncological Dispensaries, In-patient Departments, Regional Polyclinics and Medical Prophylactic Institutions is of great importance.