Saratov JOURNAL of Medical and Scientific Research

Blood status in the long-term radiation syndrome

Year: 2013, volume 9 Issue: №4 Pages: 882-890
Heading: radiation medicine Article type: Original article
Authors: Galstyan I.A., Suvorova L.A., Nadejina N.M., Kozlova M.G., Nugis V.Yu.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency

Aims: to reveal regularities of change of peripheral blood indicators in the long-term acute radiation syndrome (ARS) depending on its initial severity and existence of various somatic diseases. Material and methods. Clinical he-matologic materials from 114 patients in the long-term ARS (from 1,5 to more than 20 years after radiation accident), developed as a result of gamma beta exposure are presented. Results. In the period of the late radiation effect average values of peripheral blood are in physiological norm limits. However at some patients there are temporary superficial cytopenic conditions (thrombocytopenia — 22,7%, a leukopenia — 12,2%, a neutropenia — 13,1%, a lymphocytope-nia — 10,5%). Conclusion. As a result of a dynamic research it is revealed that in the remote terms of ARS (from 1,5 to more than 20 years after radiation) average group levels of erythrocytes, leukocytes, neutrophils and lymphocytes in blood are in limits of physiological norm. However in the individual analysis of a functional state of blood at a part of patients are noted not stable cytopenic states.

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