Влияние физических нагрузок на иммунный статус у лиц с пролапсом митрального клапана
Year: 2013, volume 9 Issue: №4 Pages: 860-862
Heading: Сardiology Article type: Original article
Authors: Maslennikova О.М., Reznichenko Т.А., Firsakova V.Yu.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Heading: Сardiology Article type: Original article
Authors: Maslennikova О.М., Reznichenko Т.А., Firsakova V.Yu.
Organization: State Scientific Research Center n.a. A.I. Burnasyan — Federal Medical Biophysical Center of Federal Medical Biological Agency
Summary:
The study aimed to identify the initial signs of immune violations at professional athletes with the mitral valve prolapse. Material and methods. For establishment of frequency of occurrence of the mitral valve prolapse as manifestations of a displaziya of connecting fibers among professional athletes 541 persons were surveyed (329 young men and 212 girls), an average age was 22,4±1,2 and 21,3±1,3 years respectively. The athletes were exposed to the echocardiography doppler in a prone position on the left side. The immune status of athletes estimated indicators of cellular and humoral immunity: quantity of leukocytes, lymphocytes, phagocyte activity of leukocytes, T indicators — and V-cellular immunity. Phagocyte activity of leukocytes (monocytes and neutrophils) blood was estimated on an indicator of a phagocyte index — number of leukocytes (at %), capable to phagocyte a test-microbe (epidermal staphylococcus). Results. The mitral valve prolapse was revealed at 132 people (24,4%), 74 young men (22,5%) and 58 girls (27,4%). At athletes with a prolapse (132 people) had changes in the immune system, being shown in decrease of levels of im-munoglobulins, total of leukocytes in comparison with athletes without prolapse are revealed. Conclusions. At athletes with the mitral valve prolapse (especially at girls) in the course of adaptation to long and considerable physical activities changes are more often shown from immune system, than athletes without heart pathology. In particular, the total of leukocytes, level of immunoglobulins A and M decreases.
Bibliography:
1. Suzdal'nickij R. S., Levando V.A. Novye podhody k poni-maniju sportivnyh stressornyh immunodeficitov // Teorija i prakti-ka fizicheskoj kul'tury. 2003. № 1. S. 18-22;
2. Fahlman M.M., Engeis H.J. Mucosal IgA and URTI in American college football players: a year longitudinal study // Med.Sci. Sports Exerc. 2005. № 3. P. 374-380;
3. Gleeson M., Bishop N.C. Elite athlete immunology: importance of nutrition // Int. J. Sports Med. 2000. Vol. 21 (1). S. 44-50;
4. Gleeson M., Pyne D.B. Special feature for the Olympics: effects of exercise on the immune system: exercise effects on mucosal immunity // Immunol. Cell Biol. 2000. Vol. 78, № 5. P. 536-544;
5. Mucci P., Durand F., Lebel V, Bousquet J., Prefaut О Basophils and exercise-induced hypoxemia in extreme athletes // Immunology and Cell Biology. 2000. Vol. 78. R. 502-509;
6. Gavrilova E.A. Stressornyj immunodeficit u sportsmenov. M.: Sovetskij sport, 2009;
7. Zhuravleva A. I. Kategorii ocenki roli svobodnoradikal'nogo okislenija pri fizicheskih nagruzkah // Vestnik sportivnoj mediciny Rossii. 1999. T. 22. S. 5-7;
8. Reznichenko ТА., Maslennikova O.M., Firsako-va V Ju. Sostojanie immunnogo statusa u molodyh lie s prolap-som mitral'nogo klapana na fone fizicheskoj nagruzki // Rossijskij kardiologicheskijzhurnal. 2013. №2(100).S. 102-103;
9. Reznichenko ТА., Maslennikova O.M., Firsako-va V Ju. Pokazateli immunnogo statusa u sportsmenov s prolap-som mitral'nogo klapana // Sportivnaja medicina: nauka i prakti-ka.2013. №1 (10). S. 232-233;
10. Sternin Ju.A., Sizjakina L.P Immunologicheskie aspekty sportivnoj dejatel'nosti //Aktual'nye voprosy terapii. 2007. №4. S. 31-34;
11. The open window of susceptibility to infection after acute exercise in healthy young male elite athletes / M.W. Kakanis, J. Peake, E.W. Brenu [et al.] // Exercise Immunology Review. 2010. Vol. 16. R. 119-137;
12. Mackinnon C.T. Chronic exercise training effects on immune function // Med. a Sci. in sports and exercise. 2000. № 32 (7). P. 369-376;
13. Meerson F.Z., Malyshev I. Ju. Fenomen adaptacionnoj stabilizacii struktur i zashhita serdca. M.: Nauka, 1993;
14. Barlow J.R. Mitral valve billowing and prolapse — an overview//Aust. N. Z. J. Med. 1992. Vol. 225. R. 541-549;
15. Calle M.C., Fernandez M. L. Effect of resistance training on the inflammatory response // Nutr. Res. Practice. 2010. № 4. R. 259-269;
16. Nieman D.C., Pedersen B.K. Exercise and the immune system Regulation, integration and adaptation // Sports Med. 1999. Vol. 27 (2). R. 73-80.
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