Saratov JOURNAL of Medical and Scientific Research

Laser thermal therapy is increasingly being used in clinical practice for cancer treatment. Its major limitation is associated with low spatial selectivity. This restriction may be excluded by the use of plasmon-resonant gold nanoparticles as photothermal

Year: 2013, volume 9 Issue: №4 Pages: 700-706
Heading: Oncology Article type: Review
Authors: Chumakov D.S., Basko M.V., Dikht N.I., Bucharskaya A.B., Rodionova Т.I., Terentyuk G.S.
Organization: Saratov State Medical University, Saratov state university
Summary:

Laser thermal therapy is increasingly being used in clinical practice for cancer treatment. Its major limitation is associated with low spatial selectivity. This restriction may be excluded by the use of plasmon-resonant gold nanoparticles as photothermal sensitizers. Tunable synthesis, unique optical properties and low toxicity make gold nanostructures promising as a therapeutic agent for cancer treatment. The research work has presented the experimental data that concern the use of plasmon photothermal therapy for the treatment of transplanted and induced tumors of laboratory animals. Taking into consideration the research results it is determined that the transition of this therapeutic technology into the clinical practice can be predicted.

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