Saratov JOURNAL of Medical and Scientific Research

The role of matrix metalloproteinases in development of psoriasis and associated comorbidity

Year: 2013, volume 9 Issue: №3 Pages: 582-584
Heading: Dermatovenerology Article type: Review
Authors: Khotko A.A.
Organization: Clinical dermatovenerologic dispensary of Ministry of Public Health of Krasnodarskiy krai
Summary:

On the basis of literary data the role of matrix metalloproteinases in many pathogenetic processes was showed. It was estimated the importance of the different types and subtypes of matrixes in the pathogenesis of psoriasis. Analysis of comorbidity was given. The status of the interstitial metabolism in patients with psoriasis with cardiovascular complications metabolic syndrome cancer, the impact of MMP on angiogenesis in psoriasis.

Bibliography:
1. Rundhaug J. Е. Matrix metalloproteinases and angiogenesis // J. Cell Mol. 2005. Vol. 9. P. 267-285; 2. Stetler-Stevenson W. G. Matrix metalloproteinases in angiogenesis: a moving terget for therapeutic intervention // J. Clin. Invest. 1999. Vol. 103, №9. P. 1237-1241; 3. Regulation of matrix metalloproteinases: an overview / S. Chakraborti, M. Mandal, S. Das [et al.] // Mol. Cell Biocnem. 2003. № 11. P. 253-269; 4. Kim W.Y.Kaelin W.G. Role of VHL gene mutation in human cancer// J. Clin. Oncol. 2004. Vol. 22. P. 4991-5004; 5. Smirnova L.M., Bilalova U.G. Metabolicheskij sindrom i psoriaz. M., 2010; 6. Matrix metalloproteinases and the regulation of tissue remodeling /A. P. McCaw, A.J. Ewald, Z. Werb// Nat. Rev. Mol. Cell. Biol. 2007. Vol. 8, № 3. P. 221-233; 7. Sternlicht and Werb, 2001; Lynch and Matrisian, 2002; Kessenbrock et al., 2010; 8. Van Lint P., Libert О Chemokine and cytokine processing by matrix metalloproteinases and its effect on leukocyte migration and inflammation // J. Biol. 2007. № 82 (6). P. 1375-1381. DOI:10.1189/jlb.0607338; 9. Brown D.L. Clinical and biochemical results of the metalloproteinase inhibition with subantimicrobial doses of doxycycline to prevent acute coronary syndromes (MIDAS) pilot trial / D.L. Brown [et al.] // Arterioscler. Thromb. Vase. Biol. 2004. Vol. 24. P. 733-738; 10. Poterjaeva O.N. Matriksnye metalloproteinazy: stroenie, reguljacija, rol» v razvitii patologicheskih sostojanij (obzor litera-tury). M., 2010; 11. Turna A.A., Toguzov R.T. Matriksnye metalloproteinazy i serdechno-sosudistye zabolevanija. M., 2008; 12. Markery serdechno-sosudistoj nedostatochnosti. URL: www.biochemmak.ru

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