Saratov JOURNAL of Medical and Scientific Research

Comparative characteristics of mammary glands cancer in humans and animals

Year: 2012, volume 8 Issue: №3 Pages: 706-711
Heading: Physiology and Pathophysiology Article type: Review
Authors: Vorobyova О.V., Terentyuk G.S., Bucharskaya A.B.
Organization: Saratov State Medical University, Chuvash State University n.a. I.N. Ulyanov

This review is devoted to a comparative analysis of receptor status, immunity, angiogenesis, metastatic mammal glands cancer expression profiling in humans and animals. Angiogenesis has been assessed by quantitative and immunohistochemical characteristics by means of evaluation of microvascular density (MVD) using Claudin-5 (CLDN-5) as a marker of vascular endothelium in tumors of mammary glands in dogs.

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