Saratov JOURNAL of Medical and Scientific Research

Effect of hyperbilirubunemia on coagulation system of blood in patients with obstructive jaundice

Year: 2012, volume 8 Issue: №2 Pages: 329-332
Heading: Surgery Article type: Original article
Authors: Tolstokorov A.S, Sarkisian Z.O.
Organization: Saratov State Medical University

Objective of the study: determination of the degree of influence of bilirubin in the blood during obstructive jaundice, on blood clotting. Methods. A retrospective study of case histories of patients with obstructive jaundice who have been treated at the Regional Hospital of Saratov in the period from 2000 to 2010. Results. The results confirm the assumption that the causes of bleeding in obstructive jaundice is hepatic failure. Conclusion. Absence of bile in the small intestine in obstructive jaundice is not the cause of bleeding. Bile acids are not involved in metabolizing fat-soluble vitamin K1

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