Saratov JOURNAL of Medical and Scientific Research

THE ESTIMATE OF A ROLE OF CORTICOSTERONUM IN REALIZATION IMMUNOSUPPRESSIVE EFFECTS AT COMBINED ACTIVITY OF ETHYLENE DICHLORIDE AND HEAVY MECHANICAL TRAUMA

Year: 2007, volume 3 Issue: №1 Pages: 51-58
Heading: Physiology and Pathophysiology Article type: Original article
Authors: Zabrodskii P. F., Kirichuk V.F., Ivanov D.U.
Organization: Saratov State Medical University
Summary:

It was established in experiments on noninbred rats that combined action of 1,2-dichloethane in a single dose 0,8 LD50 and heavy mechanical trauma the summation them immunosuppressive effects in an essential degree depends on magnifications of concentration of corticosteronum in a blood plasma of rats owing to postintoxication and posttraumatic stress-response.
Keywords: 1,2-dichloethane, heavy mechanical trauma, corticosteronum, immunosuppression, combined activity

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