Саратовский научно-медицинский ЖУРНАЛ

Методика трансартериальной химиоэмболизации при первичных и метастатических опухолях печени

Резюме:

В обзоре литературы представлены данные о методике трансартериальной химиоэмболизации — широко используемом методе лечения первичных и вторичных опухолей печени. Показана роль химиоэмболизации как неоадъювантной терапии гепатоцеллюлярного рака (ГЦР), как методики лечения нерезектабельного ГЦР и как методики лечения метастатического поражения печени. Описана морфофункциональная основа методики, преимущества суперселективного интраартериального введения цитостатиков, особенно в сочетании с ишеми-ческим воздействием на опухоль. Затронута также тема выбора химиотерапевтического агента; рассмотрены современные насыщаемые цитостатиками микросферы, которые позволяют использовать большие дозы химиотерапевтического препарата без увеличения системного эффекта и увеличивают продолжительность его воздействия на опухоль. Отмечено отсутствие корреляции наличия и тяжести постэмболизационного синдрома с успешностью процедуры.

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